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Sleep Disorders May Be Linked to Higher SUDEP Risk

Written by Ted Samson
Posted on August 19, 2026

A new study suggests that people with epilepsy who also have diagnosed sleep disorders may have a higher estimated risk for sudden unexpected death in epilepsy (SUDEP). Approximately 1 in 1,000 people with epilepsy die from SUDEP each year.

In the study, about 4.3 percent of people with a diagnosed sleep disorder were classified as having high estimated SUDEP risk on the rSUDEP-7 scale, compared with 2.3 percent of those without a sleep disorder.

The rSUDEP-7 is a seven-item clinical tool that uses factors such as seizure type and frequency to estimate a person’s relative risk of SUDEP. Relative risk means how a person’s risk compares with that of others with epilepsy.

After researchers accounted for several other factors, having a sleep disorder was associated with nearly twice the odds of being classified in the high-risk group.

SUDEP is rare overall, but the study suggests that diagnosed sleep disorders may be associated with factors linked to higher SUDEP risk.

Why Sleep Problems Matter in Epilepsy

About 80 percent of SUDEP cases happen during sleep. This is one reason doctors pay attention to nocturnal (nighttime) seizures, sleep quality, and sleep disorders such as sleep apnea.

Sleep disorders can also overlap with seizure symptoms. In some cases, poor sleep, waking up often, daytime sleepiness, or breathing problems at night may also affect seizure control and safety.

What the Study Found

Researchers reviewed the medical records of 1,506 people with active epilepsy between 2018 and 2022. Of those participants, 376 had a diagnosed sleep disorder, and 1,130 didn’t.

The researchers found that:

  • People with sleep disorders had higher estimated SUDEP risk scores, along with higher rates of death from any cause and accidents.
  • Sleep disorder diagnoses were linked with greater odds of high SUDEP risk on the rSUDEP-7 scale.
  • The two groups were similar in age, sex, living situation, epilepsy duration, epilepsy type, and the percentage who had been seizure-free for more than a year.

The researchers also noted that people with sleep disorders more often reported poor sleep quality, including waking up during the night, irregular sleep schedules, and excessive daytime sleepiness.

Important Limits To Keep in Mind

This study has some important limitations.

First, it was observational and retrospective. That means it found a link, not proof that sleep disorders directly raise SUDEP risk.

Second, the study estimated SUDEP risk rather than actual SUDEP events. It didn’t directly show that sleep disorders led to more SUDEP deaths. The findings show a link with higher rSUDEP-7 scores, not with actual SUDEP events.

Finally, the study doesn’t prove that treating a sleep disorder will lower SUDEP risk. The researchers said future prospective studies are needed to answer that question.

What This Means for People With Epilepsy

The study findings suggest sleep health may deserve more attention as part of epilepsy care. It doesn’t mean sleep disorders are the only reason SUDEP happens or that having a sleep disorder means someone is in immediate danger. But it does suggest that sleep health could be one more piece of the puzzle.

If you or a loved one with epilepsy also snores, wakes up often, feels unusually sleepy during the day, or thinks they may have a sleep disorder, consider bringing that up with a neurologist. They can help decide whether you need a sleep evaluation and how sleep may affect your epilepsy care.

4 Questions To Ask Your Doctor

  • Could a sleep disorder be affecting my seizures or my risk of SUDEP?
  • Do I have symptoms that suggest I should get a sleep evaluation or sleep study?
  • If I have nighttime seizures or poor sleep, how might that affect my treatment plan?
  • What steps can I take to improve sleep safety and seizure control?

Join the Conversation

On MyEpilepsyTeam, people share their experiences with epilepsy, get advice, and find support from others who understand.

Have sleep problems ever affected your seizures or made it harder to manage epilepsy? Let others know in the comments below.

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