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Real members of MyEpilepsyTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyEpilepsyTeam Member asked a question 💭
Missouri Valley, IA
December 12, 2025
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A MyEpilepsyTeam Member

Hey @A MyEpilepsyTeam Member When I first started Topamax over 10 years ago my weight dropped dramatically. People thought I was becoming anorexic but it was just because it reduced my hunger so much. I went from size 14 to size 8-10 (AUS/UK).
Now being menopausal and taking 2 other AEDs weight has come back hahaha but I still don't have hunger pangs- just get lightheaded and remind myself to eat something.

December 12, 2025
A MyEpilepsyTeam Member

Thanks to posters above. Topamax could help w migraines and weight gain I read. I don’t want vision problems as I have on Keppra.

December 12, 2025
A MyEpilepsyTeam Member

I have first time vision problems w Keppra. I read vision problems could occur w Topamax too.

December 12, 2025
A MyEpilepsyTeam Member

@A MyEpilepsyTeam Member It should definitely help with weight gain, it should help manage migraines. The only issues with the dosages the use for epilepsy v migraine is it can be a lot higher. So it may be a bit hit and miss for migraine headaches if you are on it for epilepsy. I'm on it for epilepsy and my dosage if 500mg which is way to high for migraines. however, I find it still helps if limit it if you do everything else correctly.

December 12, 2025
MyEpilepsyTeam

Can Topamax help with weight gain and migraines while taking Keppra?

Topamax (topiramate) is associated with weight loss rather than weight gain, which could potentially help if you're experiencing weight gain on Keppra. While Keppra is generally considered weight-neutral, some people do experience weight changes on it.

Show Full Answer

Can Topamax help with weight gain and migraines while taking Keppra?

Topamax (topiramate) is associated with weight loss rather than weight gain, which could potentially help if you're experiencing weight gain on Keppra. While Keppra is generally considered weight-neutral, some people do experience weight changes on it.

Topiramate is one of the anti-seizure medications that tends to promote weight loss rather than gain. However, it's important to discuss this with your doctor before making any medication changes.

If you're experiencing both weight gain and migraines on Keppra, your doctor can help you weigh the risks and benefits of adjusting your treatment. They may recommend:

- Lowering your Keppra dose
- Switching to a different medication like Topamax
- Adding another medication to manage side effects
- Working with a dietitian on nutrition strategies

Never stop or change your medication without talking to your doctor first, as this could affect your seizure control.

December 12, 2025

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