@A MyEpilepsyTeam Member , I’m 47 & I bet I’ve been on Depakote since my mid teens, give or take, then when trying to find a new Neurologist, after seeing my Pediatric Neurologist for almost 30 years & he started me on the Depakote, but this other Neurologist on the first visit asked me on my first visit with him if I was aware that long term use of Depakote could possibly cause Osteoporosis & I said no & so he had me do a bone density test & that showed that I have Osteopenia in my left hip & he recommended that I take Vitamin D & continued me on the Depakote. My current Neurologist still has me taking Vitamin D & still has me taking Depakote, twice a day, 750mg in the morning & 500mg at night. I had been on the same Depakote dosage for so many years of 1 500mg tablet twice a day without any problems & then suddenly in December 2018 I got a twitch in my shoulder & later that evening I had trouble breathing & whatever else & so we went to the hospital but they claimed I was just dehydrated & as months went by my arms got this awful shaking, my right leg shook sometimes & other symptoms. I didn’t have any insurance & so I couldn’t just go to the doctor & didn’t know about some services available at the time, basically, we ended up going to my Family clinic in May 2019 & my doctor saw that I hadn’t had bloodwork done in almost a & so we did that & it showed that my Depakote level was at 135 & normal is between 50 to 100 & so my dosage was adjusted & several months later the shaking stopped. So it’s good to keep up with your bloodwork cause you sure don’t want the shaking in your arms like I had. Hope you’re okay. Your friend in Texas, Becky

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