Answer Summary

Members responded to a question about which medications made their seizures worse or caused difficult side effects, with Keppra and Depakote... Read more

Members responded to a question about which medications made their seizures worse or caused difficult side effects, with Keppra and Depakote being the most commonly mentioned culprits. Several members shared that Keppra triggered absence seizures, intense irritability, mood swings, anxiety, and even suicidal thoughts, while Depakote was linked to major weight gain and worsened seizures. A recurring theme was that finding the right medication is a deeply personal journey, with many members going through multiple medications before finding one that offered better control.