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Tranxene is a prescription medication approved by the Food and Drug Administration (FDA) in 1972 to treat epilepsy. Tranxene is used in combination with other drugs to treat partial seizures that do not respond to first-line drugs. Tranxene is also known by its drug name, Clorazepate.

Tranxene should not be used by children under the age of nine years or people with narrow-angle glaucoma, psychosis, depression, or a history of hypersensitivity to benzodiazepines. Tranxene is not be suitable for use by women who are pregnant or breastfeeding. Tranxene is not frequently prescribed for older adults since it is less safe for this population than other, similar medications.

Tranxene is a member of the benzodiazepine class of drugs. Benzodiazepines are used to treat seizures, anxiety, and alcohol withdrawal. It is believed that Tranxene works in cases of epilepsy by inhibiting nerve signals.

How do I take it?
Tranxene is taken orally as a tablet one to three times a day. Your doctor will likely start you on a low dose of Tranxene and gradually increase the dosage.

Avoid driving or operating machinery until you are certain you understand how Tranxene affects you.

Drinking alcohol while taking Tranxene can intensify some side effects.

If you smoke while taking Tranxene, it can decrease the effectiveness of the drug.

Do not suddenly stop taking Tranxene. If you decide to stop taking Tranxene, consult your doctor for a plan to taper off your dose gradually.

Always follow your doctor’s instructions exactly when taking Tranxene.

In a 1987 study, 31 people with epilepsy that did not respond to other drugs were given Clorazepate (Tranxene) in addition to their current medication. Twelve people showed significant improvement in their rate of seizures. Of these, three became seizure-free after taking Clorazepate.

Side effects
Tranxene can be habit-forming.

Common side effects of Tranxene include sleepiness, dizziness, fatigue, headache, dry mouth, drooling, restlessness, aggressive behavior, and confusion.

Call your doctor if you experience vision changes, muscle tremors, skin rash, slurred speech, or difficulty walking while taking Tranxene.

Many drugs can cause allergic reactions that, in the most serious cases, can result in death. Seek immediate medical help if you experience signs of a severe allergic reaction such as difficulty breathing or swelling in the face, throat, eyes, lips or tongue.

Tranxene (Clorazepate) for Epilepsy Questions

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