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Fycompa is a prescription medication approved by the Food and Drug Administration (FDA) in 2012 for the treatment of partial seizures in people with epilepsy who are 12 years and older. Fycompa is also known by its drug name, Perampanel.

Fycompa should not be used in people with severe liver or kidney impairment. Fycompa should be used with caution in people with mild liver or kidney impairment or a history of alcohol abuse. Fycompa is not be suitable for use by women who are pregnant or breastfeeding. Fycompa is not approved for use in children under the age of 12.

Fycompa is an anticonvulsant, or drug that is used to control seizures. It is believed that Fycompa works in cases of epilepsy by inhibiting nerve signals.

How do I take it?
Fycompa is taken orally as a tablet once a day at bedtime. Your doctor will likely start you on a low dose of Fycompa and gradually increase the dosage.

Avoid driving or operating machinery until you are certain you understand how Fycompa affects you.

Fycompa may reduce the effectiveness of some forms of birth control, including oral contraceptives and implants. You may need to adopt another form of birth control while using Fycompa.

Avoid drinking alcohol while taking Fycompa.

Do not stop taking Fycompa suddenly. If you decide to stop taking Fycompa, consult your physician for a plan to taper off gradually.

Always follow your doctor’s instructions exactly when taking Fycompa.

Perampanel (Fycompa) was approved by the FDA on the basis of three clinical trials. Based on the results of the clinical trials, researchers concluded that Perampanel is more effective in controlling partial seizures than a placebo.

Side effects
Older adults may experience some side effects of Fycompa more intensely than other people.

The most serious side effects of Fycompa are psychological changes including suicidal thoughts and behavior and aggression toward others. .

Common side effects of Fycompa include sleepiness, dizziness, fatigue, nausea, constipation, vomiting, weight gain, trouble walking, falls, vertigo, aggression, anger, and irritability.
Call your doctor if you experience mood swings, changes in behavior, suicidal thoughts, chest pain, or yellowing of the skin or eyes while taking Fycompa.

Many drugs can cause allergic reactions that, in the most serious cases, can result in death. Seek immediate medical help if you experience signs of a severe allergic reaction such as difficulty breathing or swelling in the face, throat, eyes, lips or tongue.

Fycompa (Perampanel) for Epilepsy Questions

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