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Real members of MyEpilepsyTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 20
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A MyEpilepsyTeam Member

Ive been on keppra 1000mg 2 x a day for 26 years. No side effects. Just frequent urination. Your diet, drinking, smoking, illegal drugs, spicy foods, 2 much sun exposure, stress, menopause can cause it too.

September 23
A MyEpilepsyTeam Member

I was taking a higher dose of Keppra twice and day and was having a seizure every three months. This was after I stopped having a seizure once or twice every month. My doctor increased my Keppra and added an second medication. Last year I have one seizure the entire year and have only had one seizure this year.
Definitely tell your doctor every time you have a seizure. Also, don't be afraid of Keppra. Everyone is different. It works for some but not for others.
This is the only medication and the second medication I have been on.

September 23
A MyEpilepsyTeam Member

Have you updated your doctor? When you are having seizures, there is a need to reach out immediately to the doctor and update them. Do not wait for the next appointment. This is how change can come for you. Some will have you come into the office; others will make the change again without a meeting, depending on how long it's been since your last doctor's appointment. If you are not a regular at their office and the seizures keep happening, go to the ER and have it documented, and then the doctor will get you in sooner. I always called after the seizure, and I finally had success with the brain surgery. This August was 12 years seizure-free. Never give up.

September 23
MyEpilepsyTeam

Having a breakthrough seizure every few months despite being on Keppra is frustrating, but it's worth knowing there are several things that could be contributing β€” especially if they're happening in the early morning.

Early morning seizures are actually quite common and may be linked to your body's natural sleep-wake cycle Show Full Answer

Having a breakthrough seizure every few months despite being on Keppra is frustrating, but it's worth knowing there are several things that could be contributing β€” especially if they're happening in the early morning.

Early morning seizures are actually quite common and may be linked to your body's natural sleep-wake cycle, which can influence when seizures are most likely to occur. Research suggests that circadian rhythms play a real role in seizure timing.

Here are some things worth exploring with your neurologist:

- Medication timing β€” If doses are taken too far apart, levels may dip overnight. Your doctor might consider adjusting your schedule or exploring extended-release Keppra.
- Sleep quality β€” Poor or interrupted sleep is a well-known seizure trigger, not just the amount of sleep.
- Missed or late doses β€” Even occasional delays can matter more than people realize.
- Stress and fatigue β€” These are among the most commonly reported triggers by people with epilepsy.
- Alcohol use β€” Even moderate use can affect seizure risk, particularly during sleep. It's also worth keeping a seizure diary to track patterns around those episodes β€” sleep, stress, diet, and timing. Bringing that data to your neurologist could open up a real conversation about whether a dose adjustment or additional treatment might help.

Don't adjust your Keppra dose on your own though β€” always work with your doctor on any changes.

September 20

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