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A MyEpilepsyTeam Member asked a question 💭
Stockton, CA

Does anyone know if the seizure medications are related to what is taken daily? I am just wondering because a primary care doctor is trying to see how my Creatine is so high and I feel like she's trying to scare me by mentioning having kidney failure or kidney damage. This isn't true though especially when I told her that I was misdiagnosed with having high blood pressure and being a pre-diabetic. I never had them and have a lawsuit against a doctor for falsely diagnosing me with these… read more

September 3
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Answer Summary

Members explored whether creatinine levels are connected to epilepsy medications, sharing that while seizure meds may play a role, other... Read more

Members explored whether creatinine levels are connected to epilepsy medications, sharing that while seizure meds may play a role, other factors like supplements, other prescriptions, and overall kidney health are also important to consider. Several members shared personal experiences with routine blood monitoring every few months to track creatinine, and one member described working with both a neurologist and kidney doctor to adjust medication dosages after their levels climbed. A recurring theme was the value of getting a second opinion, keeping all doctors informed about every supplement and medication being taken, and using resources like drugs.com to better understand how medications interact.

A MyEpilepsyTeam Member

There more than likely just talking about the blood levels. Your body makes Creatine naturally, so you need to be careful if you do take supplements that contain it. Its completely normal for them to do these tests if you haven't had one for a while as these meds can affect the Kidneys or liver depending on what you take. If it's a med that goes via the liver the blood tests are normally every 6 months.

September 3
A MyEpilepsyTeam Member

@A MyEpilepsyTeam Member: It totally makes sense what you're saying. I just felt like the primary care doctor wasn't listening to what I had to say. Basically, I had an inflamed liver before and a previous doctor who falsely misdiagnosed me with high blood pressure and being a pre-diabetic didn't even do any blood work on me for proof of it. I went to an Urgent Care and after close to 6 years got off of the high blood pressure medication. My Creatinine came up at 1.37 mg and the normal range is supposed to be between 0.50 to 0.99 mg/dl. Back in 2024 and in 2025 my Creatinine was just fine. I only take what has been prescribed so far which is Vitamin D (due to lack of sun exposure which I disagree with this reason for it being prescribed), Centrum Multivitamin for Women, Vitamin B6, Calcium, Magnesium, and Iron (recently found out that I had Anemia for the very first time in my life). Mind you the Vitamin D, B6, Calcium, and Magnesium are all prescribed by my neurologist. I had imbalanced (not balanced) triglycerides for 17 years and bad cholesterol. I lost a bunch of weight and my original cholesterol along with my triglycerides went back to being normal. However, this primary doctor isn't listening to what I have to say and how I have been told that I went to four specialists last year and was told that I am not a Diabetic. I told them that my A1C proved in my bloodwork that I don't have Diabetes. It came up at 5.4%. I told the doctor that I believe that my anemia is a side effect from the medication of Metformin. It states that it may cause Anemia. I am going to get a second opinion from a doctor to find out because I already did bloodwork to show proof that I am not a diabetic.

September 6
MyEpilepsyTeam

These are really valid concerns, and it makes complete sense to want clarity on what's driving those lab results — especially when you've already had a frustrating experience with a misdiagnosis.

Yes, some anti-seizure medications can affect the kidneys over time, which may influence certain lab values. This is why doctors Show Full Answer

These are really valid concerns, and it makes complete sense to want clarity on what's driving those lab results — especially when you've already had a frustrating experience with a misdiagnosis.

Yes, some anti-seizure medications can affect the kidneys over time, which may influence certain lab values. This is why doctors sometimes monitor bloodwork regularly when you're on long-term epilepsy treatment.

Some medications known to require monitoring include:

- Older medications like phenytoin, phenobarbital, and carbamazepine
- Newer medications like levetiracetam (Keppra), topiramate, and zonisamide
- Some newer drugs are still being studied for long-term effects Getting a second opinion is always a reasonable and empowered step — especially when something doesn't feel right. A neurologist or a specialist familiar with your epilepsy medications would be well-placed to help connect the dots between your anti-seizure treatment and any unusual lab results.

It's worth bringing a full list of your current medications to that appointment so they can assess whether anything could be contributing to the elevated levels your doctor flagged.

September 3
A MyEpilepsyTeam Member

No it isn’t related to seizure meds . It suppose to help people with muscular Dystrophy and Heart failures.

Any time you have a question about medications. Check out www.drugs.com ..

https://www.drugs.com
September 6
A MyEpilepsyTeam Member

Your creatinine relates to your kidneys. If it is high, it means your kidneys are working overtime without rest. This is bad. I was at stage four kidney disease. I am taking a generic brand of farciga. It slows down your digestion. I also have diabetes. I am at stage three now, but my last lab results show my creatinine levels creeping up again. A couple of years ago I was at stage four. I have an appointment with my kidney doctor at the end of this year. My neurologist told me it was not my seizure meds, but my kidney doctor had her lower my Briviact from a 100 to 75mg twice a day. In January, I had a seizure in the snowstorm and went to emergency, the neurologist there increased it to 175mg twice a day. A few weeks ago my neurologist decreased it back to 100mg twice a day. Last week my primary reviewed my lab work, and saw my creatinine was increasing, and told me to stopped taking my over-the-counter iron medication ( for my anemia).

September 6

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