I've never had problems with Lamictal or Klonopin, but since I started Epidiolex I do have loose stools. My epileptologist suggested Imodium. It hasn't been bad enough for the Imodium, I changed my diet first, eating a lot more fruit and green veggies, which has had enough of an effect to make it tolerable.

The Epidiolex causes badly loose bowels, but sometimes I am very constipated also. I did not think about that as a side effect of the Lamotragine, Briviact and Onfi.

Leslie3,
I haven't had too much of a problem with the Epidiolex. Pepto Bismol is one of the nastiest tasting things I've ever ingested. I haven't had to take Imodium once so far because the diet change seems to be working. (I love cheese and eggs!) I'd be more concerned if it were uncontrollable diarrhea, which he said was the most common side effect. The only time I might have a problem is with restaurant foods, and with a fixed income that's no more than twice a month. All of these drugs and potions have their own downsides. Hair loss and osteoporosis from the Lamictal, the list of long-term Klonopin side effects is significant, the Omeprazole (for GERD) affects kidney function. I've had these conversations with my primary doc and epileptologist, and it comes down to risk vs. benefit. But yeah, I know what you mean. "Well managed" means no seizures, as close to a normal life as I can hope for. I'm nearing 70, I don't know how much "long term" I have left!

Eric,
I took some Pepto Bismol the other day because I felt so awful! I was told not to take Imodium on a regular basis. Instead, I find cheese and eggs will harden up the stool some.