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My Daughter Is On High Doses Of Keppra & Zorontin, She Is Having Rapid Weight Gain And Depression. Has Anyone Experienced This.

A MyEpilepsyTeam Member asked a question 💭
Rodney, MI

Tryna is on 2000mg of zorontin and 4000mg of Keppra, my daughter also has stickler syndrome which is a connective tissue and joint disease which has stunted her growth. At the age of 17 she is 4ft 6. She is developmentally delayed with a mentality of about a 6 yr old. Tryna is our happy laughing and usually hyperactive child. Now she gets home and is very quiet and withdrawn, little or no smiles and usually no laughing. I have talked to her to see if something was bothering her and she just says… read more

April 24, 2023
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A MyEpilepsyTeam Member

I’ve experienced this with keppra and topamax. I gained 60+ pounds, but this cocktail controlled my epilepsy. I no longer take keppra because of this. My neurologist was instrumental in me trying out new meds. I’ve lost over 80+ pounds. I’m now on zorontin and have had no side effects.
My side effects:
Keppra: weight gain
Topamax: tinnitus (ringing in ears)
Both meds: Depression
I’ve lost the weight with exercise, Accupuncture/massage and dieting; depression is a never ending battle.
I hope this helps!

April 24, 2023 (edited)
A MyEpilepsyTeam Member

I’m keeping you guys in prayer!

April 26, 2023
A MyEpilepsyTeam Member

Thank you all so much. I am waiting on the neuro to call me back regarding changing her meds

April 25, 2023
A MyEpilepsyTeam Member

Here is info on both medications,
https://www.drugs.com/keppra.html
https://www.drugs.com/mtm/ethosuximide.html

April 24, 2023

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