I live in Australia. I have family in New Zealand. (A 3 hour journey and a 2 hour time difference. I have travelled to the US twice ( both East and West Coast) and to Europ (Greece and Italy)

The simple thing to do is take them the morning you leave.
Add the usuall gap in time. (Say 12 hours then factor in the time difference.
If it is a short time difference (say 3 hours) the time zone doesntt matter.

If it's 12 hours (say NZ to England ) do the factoring for the plane trip then just take the natural time in the new location

If the plane trip is between 8 and 12 hours take one set during the flight.
If less none
If more base the second on your usual 12 hour gap.

Some folk get very regimented in taking their meds.
Your body retains a certain level over time so a journey might confuse you but it won't adversely effect your medication levels.

What are you. Traveling by. Are you going by car or bus, train or plane. actual forget that. With me I would stay at my time schedule for my meds until I get to my destination. Once I there , then wait for the next day and go by that time zone the next day.

What are you. Traveling by. Are you going by car or bus, train or plane. actual forget that. With me I would stay at my time schedule for my meds until I get to my destination. Once I there , then wait for the next day and go by that time zone the next day.

What are you. Traveling by. Are you going by car or bus, train or plane. actual forget that. With me I would stay at my time schedule for my meds until I get to my destination. Once I there , then wait for the next day and go by that time zone the next day.