Changing Medication From Immediate Release To Extended Release | MyEpilepsyTeam

Connect with others who understand.

sign up Log in
Resources
About MyEpilepsyTeam
Powered By
Real members of MyEpilepsyTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
Changing Medication From Immediate Release To Extended Release
A MyEpilepsyTeam Member asked a question 💭

I have been on Lamictal since July of last year. After we got to the dosage my doctor wanted, we found that my level runs on the low side. It still is in the therapeutic range but some days it dips low from being off by an hour when I take it and I start getting auras and absence seizures. The doctor gave me two options: take lamictal three times a day or switch to Lamictal XR. I thought there was only brand name lamictal XR so I opted for 3 times a day until I discovered lamotrigine ER a.k.a… read more

posted January 21, 2016 (edited)
•
View reactions
A MyEpilepsyTeam Member

Unfortunately, My body has to take Meds 3x's a day. I tried it but taking meds for 41 years, the body gets to handle it over time and builds up a resistance, thus more MEDS are taken.

posted January 21, 2016
A MyEpilepsyTeam Member

I don't know if 'immediate release' vs. 'extended release' will affect your body or not. It's a matter of convenience and how many times per day you want to be taking pills. You might find the following article of interest:
https://en.wikipedia.org/wiki/Time_release_tech...
I take Levetiracetim XR and am happy that I don't have to take it multiple times per day. I also don't have to worry about blood levels being too high or low. The XR keeps them at an even keel.
Your milage may vary. :-)

posted January 21, 2016
A MyEpilepsyTeam Member

I've been on the XR now for about 6 months if not longer. I was in a similar situation as yourself. I am thankful I am on it. All you can do, is try it. It's not going to hurt you. It did seem to help reduce the effects. I don't recall how long it took though. I take 300mg am and 250mg pm. I take it exactly at the same time. 7 & 7. This seems to help when I keep it like this to prevent any differences/ feeling/ symptoms.
I wish I knew about XR earlier. It might of helped me earlier and kept me from changing my dosage.
Best of luck to you.

posted January 22, 2016 (edited)
A MyEpilepsyTeam Member

I don't know if anybody is still reading this topic, but I just found it, and it was a huge help! I do know exactly why the generic and the brand vary so much, and it is not commonly known. The AMOUNT of the active ingredient is required to be the same, but they are allowed a 20% variation in the *confidence interval* measurement when the study is done to try to prove that brand and generic meds are the same. Basically, the confidence interval measures how sure you are that you got the result you thought you did. that is a HUGE variation... Being allowed a twenty percent variation is almost unbelievable to me. There's no way to know exactly why you are seeing that much of a difference in how sure you are about your result. Most people seem to be able to handle such a huge variation for most drugs, but not epilepsy meds. That has been known for a long time, but it is not always shared with the patients.

posted March 23, 2017
A MyEpilepsyTeam Member

I am also on lamictal and I had somewhat of the same issue. My doctor increased my meds a couple times and now I'm doing well. My doctor said I still have plenty of room to increase my meds if needed

posted January 22, 2016

Related content

View All
Has Anyone Else’s Seizures Stopped After Switching To Extended Release Medication?
A MyEpilepsyTeam Member asked a question 💭
Have You Ever Had A Seizure Shortly After Obtaining A Physical Injury
A MyEpilepsyTeam Member asked a question 💭
Can Your Seizure Medication Start Giving You Side Effects Despite Being On The Medication For Several Years? I Feel Sick A Few Hours Later.
A MyEpilepsyTeam Member asked a question 💭
Continue with Facebook
Continue with Google
Lock Icon Your privacy is our priority. By continuing, you accept our Terms of use, and our Health Data and Privacy policies.
Already a Member? Log in